Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions

The intronic Ig heavy chain (IgH) enhancer, which consists of the core enhancer flanked by 5′ and 3′ matrix attachment regions, has been implicated in control of IgH locus recombination and transcription. To elucidate the regulatory functions of the core enhancer and its associated matrix attachment...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Sakai, Eiko, Bottaro, Andrea, Davidson, Laurie, Sleckman, Barry P., Alt, Frederick W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1526
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