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The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway

The CBP [CREB (cAMP-response-element-binding protein)-binding protein]/p300 acetyltransferases function as transcriptional co-activators and play critical roles in cell differentiation and proliferation. Accumulating evidence shows that alterations of the CBP/p300 protein levels are linked to human...

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Main Authors: Sánchez-Molina, Sara, Oliva, José Luis, García-Vargas, Susana, Valls, Ester, Rojas, José M., Martínez-Balbás, Marian A.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550303/
https://ncbi.nlm.nih.gov/pubmed/16704373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060052
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