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Molecular and Genetic Determinants of Rous Sarcoma Virus Integrase for Concerted DNA Integration

Site-directed mutagenesis of recombinant Rous sarcoma virus (RSV) integrase (IN) allowed us to gain insights into the protein-protein and protein-DNA interactions involved in reconstituted IN-viral DNA complexes capable of efficient concerted DNA integration (termed full-site). At 4 nM IN, wild-type...

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Bibliografiske detaljer
Main Authors: Chiu, Roger, Grandgenett, Duane P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC155021/
https://ncbi.nlm.nih.gov/pubmed/12743305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6482-6492.2003
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