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Human Rhinovirus Type 16: Mutant V1210A Requires Capsid-Binding Drug for Assembly of Pentamers To Form Virions during Morphogenesis

Our laboratory has previously reported isolation of human rhinovirus type 16 (HRV16) mutants which depend on WIN 52035 to grow. A rapid rise of progeny virus infectivity occurred when drug was added late in growth cycles, suggesting that the drug-dependence lesion was at the step of virus assembly (...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Wai-Ming, Wang, Wensheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC154994/
https://ncbi.nlm.nih.gov/pubmed/12743280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6235-6244.2003
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