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Human Rhinovirus Type 16: Mutant V1210A Requires Capsid-Binding Drug for Assembly of Pentamers To Form Virions during Morphogenesis

Our laboratory has previously reported isolation of human rhinovirus type 16 (HRV16) mutants which depend on WIN 52035 to grow. A rapid rise of progeny virus infectivity occurred when drug was added late in growth cycles, suggesting that the drug-dependence lesion was at the step of virus assembly (...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Lee, Wai-Ming, Wang, Wensheng
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2003
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154994/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743280/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.11.6235-6244.2003
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