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Hepatitis B Virus X Protein and Simian Virus 5 V Protein Exhibit Similar UV-DDB1 Binding Properties To Mediate Distinct Activities

The UV-damaged DNA-binding activity protein (UV-DDB) consists of two subunits, DDB1 and DDB2, and functions in DNA repair and cell cycle regulation. The DDB1 subunit is a target for the hepatitis B virus X protein (HBx). Binding of HBx to DDB1 interferes with cell growth and viability in culture and...

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Detalhes bibliográficos
Main Authors: Leupin, Olivier, Bontron, Séverine, Strubin, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154990/
https://ncbi.nlm.nih.gov/pubmed/12743284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6274-6283.2003
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