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MD-2 Is Necessary for the Toll-Like Receptor 4 Protein To Undergo Glycosylation Essential for Its Translocation to the Cell Surface

MD-2 has been reported to be required for the translocation of the Toll-like receptor 4 (TLR4) to the cell surface. However, the mechanism by which MD-2 promotes TLR4 translocation is unknown. We identified the presence of two forms of TLR4 with different molecular masses (approximately 110 and 130...

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Autors principals: Ohnishi, Takahiro, Muroi, Masashi, Tanamoto, Ken-ichi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC154975/
https://ncbi.nlm.nih.gov/pubmed/12738639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.10.3.405-410.2003
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