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MD-2, a Novel Accessory Molecule, Is Involved in Species-Specific Actions of Salmonella Lipid A
Salmonella lipid A is inactive in human macrophages despite being potently active in murine macrophages. We investigated the molecular basis for this species-specific action of Salmonella lipid A. When murine CD14 (mCD14), mTLR4, and mMD-2 were all expressed in human monocytic THP-1 cells, these cel...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC128093/ https://ncbi.nlm.nih.gov/pubmed/12065494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3546-3550.2002 |
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