MD-2, a Novel Accessory Molecule, Is Involved in Species-Specific Actions of Salmonella Lipid A

Salmonella lipid A is inactive in human macrophages despite being potently active in murine macrophages. We investigated the molecular basis for this species-specific action of Salmonella lipid A. When murine CD14 (mCD14), mTLR4, and mMD-2 were all expressed in human monocytic THP-1 cells, these cel...

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Hlavní autoři: Muroi, Masashi, Ohnishi, Takahiro, Tanamoto, Ken-ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC128093/
https://ncbi.nlm.nih.gov/pubmed/12065494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3546-3550.2002
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