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Isolation of Mutations in the Catalytic Domain of the Snf1 Kinase That Render Its Activity Independent of the Snf4 Subunit

Activation of the Snf1 kinase requires at least two events, phosphorylation of the activation loop on threonine 210 and an Snf4-dependent process that is not completely defined. Snf4 directly interacts with a region of the regulatory domain of Snf1 that may otherwise act as an autoinhibitory domain....

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Autori principali: Leech, Anna, Nath, Nandita, McCartney, Rhonda R., Schmidt, Martin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC154852/
https://ncbi.nlm.nih.gov/pubmed/12684376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.2.265-273.2003
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