Involvement of Alpha-PAK-Interacting Exchange Factor in the PAK1–c-Jun NH(2)-Terminal Kinase 1 Activation and Apoptosis Induced by Benzo[a]pyrene

Benzo[a]pyrene [B(a)P], a potent procarcinogen found in combustion products such as diesel exhaust and cigarette smoke, has been recently shown to activate the c-Jun NH(2)-terminal kinase 1 (JNK1) and induce caspase-3-mediated apoptosis in Hepa1c1c7 cells. However, the molecules of the signaling pat...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Yoshii, Shigeto, Tanaka, Masamitsu, Otsuki, Yoshiro, Fujiyama, Toshiharu, Kataoka, Hideki, Arai, Hajime, Hanai, Hiroyuki, Sugimura, Haruhiko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC99857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11564864/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.20.6796-6807.2001
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