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Novel Small-Molecule Inhibitors of RNA Polymerase III

A genetic approach utilizing the yeast Saccharomyces cerevisiae was used to identify the target of antifungal compounds. This analysis led to the identification of small molecule inhibitors of RNA polymerase (Pol) III from Saccharomyces cerevisiae. Three lines of evidence show that UK-118005 inhibit...

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Detalhes bibliográficos
Main Authors: Wu, Liping, Pan, Jing, Thoroddsen, Vala, Wysong, Deborah R., Blackman, Ronald K., Bulawa, Christine E., Gould, Alexandra E., Ocain, Timothy D., Dick, Lawrence R., Errada, Patrick, Dorr, Patrick K., Parkinson, Tanya, Wood, Tony, Kornitzer, Daniel, Weissman, Ziva, Willis, Ian M., McGovern, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154847/
https://ncbi.nlm.nih.gov/pubmed/12684375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.2.256-264.2003
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