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Ceramide/Long-Chain Base Phosphate Rheostat in Saccharomyces cerevisiae: Regulation of Ceramide Synthesis by Elo3p and Cka2p

Sphingolipid precursors, namely, ceramide and long-chain base phosphates (LCBPs), are important growth regulators with often opposite effects on mammalian cells. A set of enzymes that regulate the levels of these precursors, referred to as a ceramide/LCBP rheostat, is conserved in all eukaryotes. In...

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Main Authors: Kobayashi, Scott D., Nagiec, Marek M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC154838/
https://ncbi.nlm.nih.gov/pubmed/12684378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.2.284-294.2003
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