Acyl-CoA-binding protein, Acb1p, is required for normal vacuole function and ceramide synthesis in Saccharomyces cerevisiae.

In the present study, we show that depletion of acyl-CoA-binding protein, Acb1p, in yeast affects ceramide levels, protein trafficking, vacuole fusion and structure. Vacuoles in Acb1p-depleted cells are multi-lobed, contain significantly less of the SNAREs (soluble N -ethylmaleimide-sensitive fusion...

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Detalhes bibliográficos
Main Authors: Faergeman, Nils J, Feddersen, Søren, Christiansen, Janne K, Larsen, Morten K, Schneiter, Roger, Ungermann, Christian, Mutenda, Kudzai, Roepstorff, Peter, Knudsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224232/
https://ncbi.nlm.nih.gov/pubmed/15032750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031949
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