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Reconstruction of Mycobacterial Dehalogenase Rv2579 by Cumulative Mutagenesis of Haloalkane Dehalogenase LinB

The homology model of protein Rv2579 from Mycobacterium tuberculosis H37Rv was compared with the crystal structure of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26, and this analysis revealed that 6 of 19 amino acid residues which form an active site and entrance tunnel are differ...

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Bibliografski detalji
Glavni autori: Nagata, Yuji, Prokop, Zbyněk, Marvanová, Soňa, Sýkorová, Jana, Monincová, Marta, Tsuda, Masataka, Damborský, Jiří
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC154798/
https://ncbi.nlm.nih.gov/pubmed/12676719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.4.2349-2355.2003
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