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Crystal structure of a dimeric chymotrypsin inhibitor 2 mutant containing an inserted glutamine repeat

We have constructed mutants of chymotrypsin inhibitor 2 with short glutamine repeats inserted into its inhibitory loop. These mutants oligomerize when expressed in Escherichia coli. The dimer of a mutant with four glutamines now has been crystallized, and its structure has been solved by molecular r...

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Detalhes bibliográficos
Main Authors: Chen, Yu Wai, Stott, Kelvin, Perutz, Max F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15450/
https://ncbi.nlm.nih.gov/pubmed/9990011
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