PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance

Protein targeting to glycogen (PTG) is a scaffolding protein that targets protein phosphatase 1α (PP1α) to glycogen, and links it to enzymes involved in glycogen synthesis and degradation. We generated mice that possess a heterozygous deletion of the PTG gene. These mice have reduced glycogen stores...

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Publié dans:	J Clin Invest
Auteurs principaux:	Crosson, Sean M., Khan, Ahmir, Printen, John, Pessin, Jeffrey E., Saltiel, Alan R.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 2003
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154451/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727934/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17975
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