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PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance

Protein targeting to glycogen (PTG) is a scaffolding protein that targets protein phosphatase 1α (PP1α) to glycogen, and links it to enzymes involved in glycogen synthesis and degradation. We generated mice that possess a heterozygous deletion of the PTG gene. These mice have reduced glycogen stores...

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Autors principals: Crosson, Sean M., Khan, Ahmir, Printen, John, Pessin, Jeffrey E., Saltiel, Alan R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC154451/
https://ncbi.nlm.nih.gov/pubmed/12727934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317975
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