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A functional androgen receptor is not sufficient to allow estradiol to protect bone after gonadectomy in estradiol receptor–deficient mice

Although the role of estradiol in maintaining bone mass is well established, the relative contributions of the estradiol receptors ERα and ERβ and of the androgen receptor (AR) remain controversial. To determine the role of ERα-mediated, ERβ-mediated, and non–ER-mediated mechanisms in maintaining bo...

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Autors principals: Sims, Natalie A., Clément-Lacroix, Philippe, Minet, Dominique, Fraslon-Vanhulle, Caroline, Gaillard-Kelly, Martine, Resche-Rigon, Michèle, Baron, Roland
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC154447/
https://ncbi.nlm.nih.gov/pubmed/12727923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317246
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