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A functional androgen receptor is not sufficient to allow estradiol to protect bone after gonadectomy in estradiol receptor–deficient mice

Although the role of estradiol in maintaining bone mass is well established, the relative contributions of the estradiol receptors ERα and ERβ and of the androgen receptor (AR) remain controversial. To determine the role of ERα-mediated, ERβ-mediated, and non–ER-mediated mechanisms in maintaining bo...

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Bibliografiske detaljer
Main Authors: Sims, Natalie A., Clément-Lacroix, Philippe, Minet, Dominique, Fraslon-Vanhulle, Caroline, Gaillard-Kelly, Martine, Resche-Rigon, Michèle, Baron, Roland
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154447/
https://ncbi.nlm.nih.gov/pubmed/12727923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317246
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