The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance

Insulin receptors (IRs) on vascular endothelial cells have been suggested to participate in insulin-regulated glucose homeostasis. To directly address the role of insulin action in endothelial function, we have generated a vascular endothelial cell IR knockout (VENIRKO) mouse using the Cre-loxP syst...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Vicent, David, Ilany, Jacob, Kondo, Tatsuya, Naruse, Keiko, Fisher, Simon J., Kisanuki, Yaz Y., Bursell, Sven, Yanagisawa, Masashi, King, George L., Kahn, C. Ronald
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI15211
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