The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance

Insulin receptors (IRs) on vascular endothelial cells have been suggested to participate in insulin-regulated glucose homeostasis. To directly address the role of insulin action in endothelial function, we have generated a vascular endothelial cell IR knockout (VENIRKO) mouse using the Cre-loxP syst...

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Detalhes bibliográficos
Main Authors: Vicent, David, Ilany, Jacob, Kondo, Tatsuya, Naruse, Keiko, Fisher, Simon J., Kisanuki, Yaz Y., Bursell, Sven, Yanagisawa, Masashi, King, George L., Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154437/
https://ncbi.nlm.nih.gov/pubmed/12727929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315211
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