Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes

Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-CoA reductase inhibitors) are being studied as possible candidates for multiple sclerosis (MS) therapy. The pathogenesis of MS is unclear. One theory suggests that the development of autoimmune lesions...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zeinstra, Esther, Wilczak, Nadine, Chesik, Daniel, Glazenburg, Lisa, Kroese, Frans GM, De Keyser, Jacques
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2006
Θέματα:
Short Report
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544322/
https://ncbi.nlm.nih.gov/pubmed/16859542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-3-16
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