Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes

Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-CoA reductase inhibitors) are being studied as possible candidates for multiple sclerosis (MS) therapy. The pathogenesis of MS is unclear. One theory suggests that the development of autoimmune lesions...

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Detalhes bibliográficos
Main Authors: Zeinstra, Esther, Wilczak, Nadine, Chesik, Daniel, Glazenburg, Lisa, Kroese, Frans GM, De Keyser, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544322/
https://ncbi.nlm.nih.gov/pubmed/16859542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-3-16
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