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Cox-2: where are we in 2003? - Cardiovascular risk and Cox-2 inhibitors

Selective cyclooxygenase-2 (COX-2) inhibitors were developed to reduce the gastrointestinal toxicity of conventional nonsteroidal anti-inflammatory agents. However, COX-2 inhibitors decrease prostacyclin production and may disrupt the normal homeostatic balance, leading to a prothrombotic state and...

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Detalles Bibliográficos
Publicado en:Arthritis Res Ther
Principais autores: Mukherjee, Debabrata, Topol, Eric J
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154429/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12716442/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar609
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