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Cox-2: where are we in 2003? - Cardiovascular risk and Cox-2 inhibitors

Selective cyclooxygenase-2 (COX-2) inhibitors were developed to reduce the gastrointestinal toxicity of conventional nonsteroidal anti-inflammatory agents. However, COX-2 inhibitors decrease prostacyclin production and may disrupt the normal homeostatic balance, leading to a prothrombotic state and...

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Detalhes bibliográficos
Main Authors: Mukherjee, Debabrata, Topol, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154429/
https://ncbi.nlm.nih.gov/pubmed/12716442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar609
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