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Ebp1 isoforms distinctively regulate cell survival and differentiation
Ebp1, an ErbB3 receptor-binding protein, inhibits the proliferation and induces the differentiation of human cancer cells. Ebp1 binds nuclear Akt and prevents DNA fragmentation by inhibiting caspase-activated DNase. Here, we show that Ebp1 possesses two different isoforms, p48 and p42, which differe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544149/ https://ncbi.nlm.nih.gov/pubmed/16832058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602923103 |
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