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Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival
Nucleophosmin/B23 is a major multifunctional nucleolar phosphoprotein that plays a critical role in ribosome biogenesis and cell proliferation. Arf tumor suppressor binds B23 and enhances its sumoylation. However, the biological effects of this event remain unknown. Here we show that B23 is sumoylat...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1887583/ https://ncbi.nlm.nih.gov/pubmed/17535915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701806104 |
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