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Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks

Cytosine methylation at CpG dinucleotides contributes to the epigenetic maintenance of gene silencing. Dynamic reprogramming of DNA methylation patterns is believed to play a key role during development and differentiation in vertebrates. The mechanisms of DNA demethylation remain unclear and contro...

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Bibliografiska uppgifter
Huvudupphovsmän: Kress, Clémence, Thomassin, Hélène, Grange, Thierry
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544051/
https://ncbi.nlm.nih.gov/pubmed/16840560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601793103
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