Natural Variation in the Microcystin Synthetase Operon mcyABC and Impact on Microcystin Production in Microcystis Strains

Toxic Microcystis strains often produce several isoforms of the cyclic hepatotoxin microcystin, and more than 65 isoforms are known. This has been attributed to relaxed substrate specificity of the adenylation domain. Our results show that in addition to this, variability is also caused by genetic v...

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Bibliographic Details
Main Authors: Mikalsen, Bjørg, Boison, Gudrun, Skulberg, Olav M., Fastner, Jutta, Davies, William, Gabrielsen, Tove M., Rudi, Knut, Jakobsen, Kjetill S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Population Genetics and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC154389/
https://ncbi.nlm.nih.gov/pubmed/12700256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.9.2774-2785.2003
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