Natural Variation in the Microcystin Synthetase Operon mcyABC and Impact on Microcystin Production in Microcystis Strains

Toxic Microcystis strains often produce several isoforms of the cyclic hepatotoxin microcystin, and more than 65 isoforms are known. This has been attributed to relaxed substrate specificity of the adenylation domain. Our results show that in addition to this, variability is also caused by genetic v...

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Main Authors: Mikalsen, Bjørg, Boison, Gudrun, Skulberg, Olav M., Fastner, Jutta, Davies, William, Gabrielsen, Tove M., Rudi, Knut, Jakobsen, Kjetill S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Population Genetics and Evolution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154389/
https://ncbi.nlm.nih.gov/pubmed/12700256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.9.2774-2785.2003
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