Identification of a series of CCK-2 receptor nonpeptide agonists: Sensitivity to stereochemistry and a receptor point mutation
The search for small-molecule drugs that act at peptide hormone receptors has resulted in the identification of a wide variety of antagonists. In contrast, the discovery of nonpeptide agonists has been far more elusive. We have used a constitutively active mutant of the cholecystokinin 2 receptor (C...
I tiakina i:
| I whakaputaina i: | Proc Natl Acad Sci U S A |
|---|---|
| Ngā kaituhi matua: | , , , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
National Academy of Sciences
2003
|
| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0831223100 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|