Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)

The tumor suppressor p53 is regulated in part by binding to cellular proteins. We used p53 as bait in the yeast two-hybrid system and isolated homeodomain-interacting protein kinase 1 (HIPK1) as a p53-binding protein. Deletion analysis showed that amino acids 100–370 of p53 and amino acids 885-1093...

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Autors principals: Kondo, Seiji, Lu, Ying, Debbas, Michael, Lin, Athena W., Sarosi, Ildiko, Itie, Annick, Wakeham, Andrew, Tuan, JoAnn, Saris, Chris, Elliott, Gary, Ma, Weili, Benchimol, Samuel, Lowe, Scott W., Mak, Tak Wah, Thukral, Sushil K.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC154362/
https://ncbi.nlm.nih.gov/pubmed/12702766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0530308100
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