Cancer-related changes in prostate DNA as men age and early identification of metastasis in primary prostate tumors
Using statistical analyses of Fourier transform-IR spectra, we show that DNA of the histologically normal prostates of men 16–80 years old undergoes structural changes in the bases and backbone with increasing age. Of the older men (ages 55–80), 42% exhibited a DNA phenotype mimicking that of primar...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12702759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0931396100 |
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