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PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells

PD-L1 and PD-L2 are ligands for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery. We find that PD-L1 is highly expressed on inflammatory macrophages as compared with resident peritoneal macrophages but can be induced on resident macrophage...

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Detalhes bibliográficos
Main Authors: Loke, P'ng, Allison, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154346/
https://ncbi.nlm.nih.gov/pubmed/12697896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0931259100
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