The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

The membrane-bound glycoprotein dipeptidyl peptidase IV (DP IV, CD26) is a unique multifunctional protein, acting as receptor, binding and proteolytic molecule. We have determined the sequence and 1.8 Å crystal structure of native DP IV prepared from porcine kidney. The crystal structure reveals a 2...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Proc Natl Acad Sci U S A
Huvudupphov:	Engel, Michael, Hoffmann, Torsten, Wagner, Leona, Wermann, Michael, Heiser, Ulrich, Kiefersauer, Reiner, Huber, Robert, Bode, Wolfram, Demuth, Hans-Ulrich, Brandstetter, Hans
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	National Academy of Sciences 2003
Ämnen:	Biological Sciences
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12690074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0230620100
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!