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Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

DNA double-strand breaks (DSBs) are generally accepted to be the most biologically significant lesion by which ionizing radiation causes cancer and hereditary disease. However, no information on the induction and processing of DSBs after physiologically relevant radiation doses is available. Many of...

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Autori principali: Rothkamm, Kai, Löbrich, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC154297/
https://ncbi.nlm.nih.gov/pubmed/12679524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0830918100
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