Sarcolipin regulates sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) by binding to transmembrane helices alone or in association with phospholamban

Phospholamban (PLN), a regulator of sarco(endo)plasmic reticulum Ca(2+)-ATPases (SERCAs), interacts with both the cytosolic N domain and transmembrane helices M2, M4, M6, and M9 of SERCA. Amino acids in the transmembrane domain of PLN that are predicted to interact with SERCA1a are conserved in sarc...

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Bibliographische Detailangaben
Hauptverfasser: Asahi, Michio, Sugita, Yuji, Kurzydlowski, Kazimierz, De Leon, Stella, Tada, Michihiko, Toyoshima, Chikashi, MacLennan, David H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154294/
https://ncbi.nlm.nih.gov/pubmed/12692302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0330962100
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