Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2

Angiopoietin-2 (Ang2) appears to be a naturally occurring antagonist of the endothelial receptor tyrosine kinase Tie2, an important regulator of vascular stability. Destabilization of the endothelium by Ang2 is believed to potentiate the actions of proangiogenic growth factors. To investigate the sp...

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Bibliografiska uppgifter
Huvudupphovsmän: White, Rebekah R., Shan, Siqing, Rusconi, Christopher P., Shetty, Geetha, Dewhirst, Mark W., Kontos, Christopher D., Sullenger, Bruce A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2003
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC154292/
https://ncbi.nlm.nih.gov/pubmed/12692304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0831159100
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