Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system

Ataxia-telangiectasia is a hereditary multisystemic disease resulting from mutations of ataxia telangiectasia, mutated (ATM) and is characterized by neurodegeneration, cancer, immune defects, and hypersensitivity to ionizing radiation. The molecular details of ATM function in the nervous system are...

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Detalhes bibliográficos
Main Authors: Chong, Miriam J., Murray, Michael R., Gosink, Eric C., Russell, Helen R. C., Srinivasan, Anu, Kapsetaki, Manuela, Korsmeyer, Stanley J., McKinnon, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15426/
https://ncbi.nlm.nih.gov/pubmed/10639175
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