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Individual variation of anti-Sm autoantibodies in the MRL/MP-lpr/lpr mouse: age-related increase in diversity.

The prevalence and diversity of anti-Sm antibodies (which are a marker of human lupus) were investigated in MRL/MP-lpr/lpr mice. The low prevalence of anti-Sm reported by other workers was confirmed. Anti-Sm antibodies bound to either the 28 kD or both 28 and 16 kD polypeptides on immunoblots. Antib...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Williams, D G, Brennan, F M, Stocks, M R, Maini, R N
Format: Artigo
Langue:Inglês
Publié: 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542507/
https://ncbi.nlm.nih.gov/pubmed/3780041
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