Regulation of interleukin 2 and interleukin 2 receptor gene expression in human T cells: I. Effect of Ca2+-ionophore on phorbol myristate acetate co-stimulated cells.

Human peripheral blood T lymphocytes were treated with phorbol myristate acetate (PMA), an activator of protein kinase C (PKC) activity, and with the calcium ionophore A23187. The resulting accumulation of specific mRNA for interleukin 2 (IL-2) and interleukin 2 receptor (IL-2R), as well as IL-2 sec...

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Bibliographic Details
Main Authors: Chopra, R K, Nagel, J E, Chrest, F J, Boto, W M, Pyle, R S, Dorsey, B, McCoy, M, Holbrook, N, Adler, W H
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542395/
https://ncbi.nlm.nih.gov/pubmed/3115657
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