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The differential mobilization of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187.

Phorbol myristate acetate (PMA, 2 to 100 ng/ml) and ionophore A23187 (10(-7) to 10(-6) M) cause human neutrophils to release up to 50% of the granule-associated enzyme lysozyme extracellularly without release of beta-glucuronidase or the cytoplasmic enzyme LDH. When azurophil and specific granules a...

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Autores principales: Wright, D. G., Bralove, D. A., Gallin, J. I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1977
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2032029/
https://ncbi.nlm.nih.gov/pubmed/322507
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