RNase T1 mediated base-specific cleavage and MALDI-TOF MS for high-throughput comparative sequence analysis

Here we devise a new method for high-throughput comparative sequence analysis. The developed protocol comprises a homogeneous in vitro transcription/RNase cleavage system with the accuracy and data acquisition speed of matrix-assisted laser desorption/ionization coupled with time-of-flight mass spec...

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Bibliografische Detailangaben

Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Hartmer, Ralf, Storm, Niels, Boecker, Sebastian, Rodi, Charles P., Hillenkamp, Franz, Jurinke, Christian, van den Boom, Dirk
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2003
Schlagworte:	NAR Methods Online
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154235/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12711692/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng047
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