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RNase T1 mediated base-specific cleavage and MALDI-TOF MS for high-throughput comparative sequence analysis

Here we devise a new method for high-throughput comparative sequence analysis. The developed protocol comprises a homogeneous in vitro transcription/RNase cleavage system with the accuracy and data acquisition speed of matrix-assisted laser desorption/ionization coupled with time-of-flight mass spec...

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Autors principals: Hartmer, Ralf, Storm, Niels, Boecker, Sebastian, Rodi, Charles P., Hillenkamp, Franz, Jurinke, Christian, van den Boom, Dirk
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC154235/
https://ncbi.nlm.nih.gov/pubmed/12711692
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