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HMG box transcription factor TCF-4’s interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells

Members of the Tcf/Lef family of the HMG box transcription factors are nuclear effectors of the Wnt signal transduction pathway. Upon Wnt signaling, TCF/LEF proteins interact with β-catenin and activate transcription of target genes, while, in the absence of the Wnt signal, TCFs function as transcri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Valenta, Tomas, Lukas, Jan, Korinek, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154232/
https://ncbi.nlm.nih.gov/pubmed/12711682
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