The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs

Human thymine-DNA glycosylase (TDG) is well known to excise thymine and uracil from G·T and G·U mismatches, respectively, and was therefore proposed to play a central role in the cellular defense against genetic mutation through spontaneous deamination of 5-methylcytosine and cytosine. In this study...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Hardeland, Ulrike, Bentele, Marc, Jiricny, Josef, Schär, Primo
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2003
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154230/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12711670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg344
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