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The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs

Human thymine-DNA glycosylase (TDG) is well known to excise thymine and uracil from G·T and G·U mismatches, respectively, and was therefore proposed to play a central role in the cellular defense against genetic mutation through spontaneous deamination of 5-methylcytosine and cytosine. In this study...

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Udgivet i:Nucleic Acids Res
Principais autores: Hardeland, Ulrike, Bentele, Marc, Jiricny, Josef, Schär, Primo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154230/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12711670/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg344
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