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The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs
Human thymine-DNA glycosylase (TDG) is well known to excise thymine and uracil from G·T and G·U mismatches, respectively, and was therefore proposed to play a central role in the cellular defense against genetic mutation through spontaneous deamination of 5-methylcytosine and cytosine. In this study...
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Huvudupphovsmän: | , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
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Oxford University Press
2003
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Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC154230/ https://ncbi.nlm.nih.gov/pubmed/12711670 |
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