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Specific chromosome 1 breaks induced by human cytomegalovirus

Human cytomegalovirus (HCMV) is the major viral cause of birth defects and a serious problem for immunocompromised individuals. Here we show that infection of cells with HCMV during the S-phase of the cell cycle results in two specific chromosome 1 breaks at positions 1q42 and 1q21. We demonstrate t...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Fortunato, Elizabeth A., Dell'Aquila, Marie L., Spector, Deborah H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.853
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