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Failure of the H2 antagonist cimetidine to reverse parasite antigen-specific lymphocyte unresponsiveness in experimental filariasis.
Histamine is known to mediate potent immunosuppressive effects on lymphocyte function. In jirds infected with Brugia pahangi decreased mitogen and parasite antigen responsiveness are associated with the presence of histamine binding regulatory cells. The present study was thus designed to investigat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1541715/ https://ncbi.nlm.nih.gov/pubmed/3219801 |
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