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Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes.

The exposure of human T-cell clones to supra-immunogenic concentrations of peptide antigen in the absence of accessory cells induces antigen-specific unresponsiveness. Using this model we have investigated the ability of cytokines to modulate the induction of, or reversal of, T-cell tolerance. Our f...

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Detalhes bibliográficos
Main Authors: Essery, G, Feldmann, M, Lamb, J R
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385051/
https://ncbi.nlm.nih.gov/pubmed/2457547
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