In vivo effects of C3a on neutrophils and its contribution to inflammatory lung processes in a guinea-pig model.

C3a, when injected intravenously in guinea-pigs, caused a rapid drop of circulating neutrophils and platelets. The neutropenia was reversible and followed by a neutrophilia, which reached about 200% of baseline values. Upon challenge with octa- and hexapeptide, mimicking the C-terminal sequence of C...

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Bibliografiske detaljer
Main Authors: Hoffmann, T, Böttger, E C, Baum, H P, Messner, M, Hadding, U, Bitter-Suermann, D
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541683/
https://ncbi.nlm.nih.gov/pubmed/3260158
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